Role of PET/CT in the follow-up of postoperative and/or post-therapy cancer rectum: comparison with pelvic MRI

Abstract Background In locally advanced rectal cancer, many imaging modalities are used, for example 18F-2-fluoro-2-deoxy-d-glucose (18F-FDG) positron emission tomography-computed tomography (PET-CT) and MRI. The aim of our study is to compare the diagnostic accuracy 18 F-FDG-PET/CT & pelvic MRI; as well investigate possible added value using combined MRI PET-CT assessment tumor response. Results Regarding presence local tumor, both PET CT showed perfect agreement with 97.1% overall accuracy, while in N category, higher specificity but lower sensitivity than was superior PET/CT detecting extension nearby organs; owing more anatomical details regarding involvement mesorectal fascia EMVI. Almost total noticed evaluating post-therapy postoperative complications. Conclusion For cancer (pT3–4 N0 M0 or any T N1 M0), a multimodality strategy has been shown be best option evaluate disease process, criteria that were based on morphology, glucose uptake, instead SUV alone reassessment changes.